April 17, 1887 born in Nicaragua, Clodomiro Picado Twight, was an outstanding Costa Rican scientist internationally recognized for his research and discoveries.

On this day (April 17), 1887, Clodomiro Picado Twight was born in Nicaragua, he was an outstanding Costa Rican scientist internationally recognized for his research and discoveries.
Although he was born in Nicaragua, his parents were from Costa Rica where they returned two years after his birth and it was in Costa Rica that Clodomiro began his studies.
In 1908, the Costa Rican Congress, on the recommendation of his high school and high school teachers, offered him a scholarship to study in Paris. In 1912 he received the diploma of Higher Studies in Botany at the Sorbonne and the doctorate is carried out at the University of Paris, receiving the diploma on November 18, 1913. That same year he was admitted to the Pasteur Institute in Paris and the Colonial Institute of that city.


His varied experimental work allowed him to publish more than 100 investigations and books, both in his country and in France, on various aspects of science, one of the greatest legacies scientists from Latin America.

His eclectic works include analysis of infectious diseases, the quality of drinking water, the pathophysiology of the thyroid, and aging.

But one of his greatest contributions was in the area of ​​ ophidism , as poisoning caused by snake bites is called.

In March 2000, doctors at the Hospital San Juan de Dios (in San José, Costa Rica) published a manuscript by Dr. Clorito Picado, in which he relates his experiences between 1915 and 1927 on the inhibitory action of fungi of the genus Penicillium sp on the growth of staphylococci and streptococci (bacteria that cause infections). Due to the above, it is recognized as one of the precursors of the antibiotic penicillin, discovered by Fleming in 1928. The report with the results of the treatments performed with penicillin by Dr. Picado were published by the Biological Society of Paris in 1927.

What Picado used to treat these patients was a substance extracted from fungi of the genus Saccharomyces , not the Penicillium, from which it comes the penicillin. Although Saccharomyces had curative effects, Picado was unable to reveal why they were effective.

How curious to comment that in n 1998 the Central Bank of Costa Rica issued a 2000 colones bill with his effigy.
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- Hello sir
- hello
- what do you want?
- I wish peace in the world
- very well, on the third floor
- really?
- no, I'm hesitating for hesitating
- sorry, I wish for a live coral snake
- a poisonous snake?
- yes, I need to milk her
- do you milk snakes?
- yes, to create antidotes
- how interesting
- thanks, do you have any?
- no, this is the bakery
- oh, well, give me a loaf of bread

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